Synthetically good cholesterol

Forget statins, could a synthetic version of "good cholesterol" (high density lipoprotein) be the answer to fighting a problematic metabolism? Chad Mirkin and colleagues at Northwestern University working with Shad Thaxton in Northwestern's Feinberg School of Medicine have designed and built a material they refer to as a "cholesterol sponge". "Drugs that lower the bad cholesterol, LDL, are available, and you can lower LDL through [changes in] your diet, but it is difficult to raise the good cholesterol, HDL," explains Mirkin. "We are hopeful that our synthetic HDL will one day help fill this gap in useful therapeutics."