The American Chemical Society named pioneering carbohydrate research by Carl and Gerty Cori a National Historic Chemical Landmark on September 21. During the 1920s, the Coris worked at Washington University in St. Louis and conducted a series of pioneering studies that led to our current understanding of how sugars are metabolized and the role this plays in diabetes. The pair won the Nobel in Physiology or Medicine in 1947 for the development of what became known as the "Cori cycle." In this process the body converts glucose into glycogen for storage. The Coris isolated and purified many of the enzymes involved in glucose metabolism, and their work ultimately advanced scientific understanding of metabolic regulation. The American Chemical Society established the chemical landmarks program in 1992 to recognize seminal events in the history of chemistry and to increase public awareness of the contributions of chemistry to society.