Simpler synthesis

Decarboxylative alkenylation can readily convert carboxylic acids into alkenes, thanks to research by chemists at The Scripps Research Institute in California, USA. Phil Baran's team suggests the simplified method really changes the way he thinks about making molecules. Baran's work displaces the multistep reactions of decades past, including the Wittig reaction invented in 1954. “Organic chemists have endured this burdensome 'analog' process for decades with little complaint,” Baran says. “Now with this new method we’re bringing olefination into the digital era.”