A sharper contrast

Better contrast agents for magnetic resonance imaging could emerge from research into a new class of materials being developed by Wenbin Lin of the University of North Carolina at Chapel Hill. Lin and his colleagues have being developing nanoscale metal-organic frameworks (NMOFs) since 2006, which are intrinsically biodegradable, and have high porosity, which makes them ideal for targeted delivery of entrapped agents. These new agents could transport gadolinium salts to a site of interest in the body and so require less contrast agent per scan.