Phthalate plasticizers are controversial because of concerns about their impact on the environment and human health. Alternatives such as 1,2-cyclohexane dicarboxylic acid diisononyl ester, which has the trade name "DINCH", an aliphatic ester, are now commonly used in the manufacture of flexible plastic articles in sensitive application areas such as toys, medical devices and food packaging. However, according to scientists at McGill University in Canada, there have been no publicly available peer-reviewed data on this compound's toxicology. A study carried out by the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal, suggests that DINCH has biological effects on metabolic processes in mammals. The findings, published in the journal Environmental Research, could have implications for health and safety.
The plasticity of safety