Nobel science

The 2015 Nobel Prize in Chemistry goes to Tomas Lindahl of the Francis Crick Institute and Clare Hall Laboratory, Hertfordshire, UK, Paul Modrich of the Howard Hughes Medical Institute and Duke University School of Medicine, Durham and Aziz Sancar of the University of North Carolina, Chapel Hill, North Carolina, USA, “for mechanistic studies of DNA repair". The DNA in our cells are constantly bombarded and damaged by oxidizing agents, radiation and other stressors. This year's chemistry prize recognizes research that mapped out, at the molecular level, the DNA repair systems that safeguard our genetic code. The work offered fundamental insights into the workings of the living cell and continues to point the way to new approaches to treating diseases that can result from failure of the repair mechanisms, including cancer.