New route to carbon-carbon bonds

A ridiculously simple route to new carbon-carbon bonds has been developed by Phil Baran from Scripps Research Institute in San Diego, USA, and colleagues. Baran’s colleagues at Bristol-Myers Squibb in New Jersey are now using and optimizing the active ester reaction developed by the Baran team. "This is pure translational chemistry: from invention to application in drug discovery in less than three months," Baran is reported as saying.