Could an unhyped finding for a Chinese herb lead to a very desirable treatment for peanut allergy? What happens though if some people turn out to be allergic to the herb? "Food Allergy Herbal Formula" has been tested in an animal model by researchers at the Mount Sinai Medical Center and Johns Hopkins University with funding by private foundations and government grants rather than any manufacturer or business interest. The results appeared in the Journal of Allergy and Clinical Immunology. The researchers had tested FAHF-1 on a mouse model of peanut allergy and demonstrated that it blocks anaphylaxis as well as reducing mast cell degranulation, histamine release, peanut-specific serum IgE levels, and Th2 cytokine secretion. However, the first formulation tested, FAHF-1, which contained wild ginger and so toxic aristolochic acid and Fu zi, which contains poisonous aconite. To make a clinically viable preparation, FAHF-2, the researchers removed these two ingredients and demonstrated similar efficacy. The researchers have tested the remaining ingredients in isolation but found only marginal effects, apparently there is a synergistic effect of the active ingredients.
Herbal synergy and peanut allergy