Fungal inhibitor turns cancer killer

A common treatment for athlete's foot and jock itch, griseofulvin, looks set to to make its debut as a new cancer treatment. Researchers at the Indian Institute of Technology Bombay and the University of California Santa Barbara, have tested the compound against cancer cell lines in the laboratory and found that it kills cancer cells via a similar mechanism as that responsible for the activity of paclitaxel and vinblastine - suppressing microtubule dynamics. The researchers suggest that a mild dose of griseofulvin could be used to bolster conventional anticancer drugs and so provide a therapeutic advantage for the treatment of certain tumors.