Chemistry was the most important science for Alfred Nobel’s own work. The development of his inventions as well as the industrial processes he employed were based upon chemical knowledge. The Royal Swedish Academy of Sciences this year awarded the Nobel Prize in Chemistry jointly to Martin Karplus Université de Strasbourg, France and Harvard University, Cambridge, MA, USA, Michael Levitt Stanford University School of Medicine, Stanford, CA, USA and Arieh Warshel University of Southern California, Los Angeles, CA, USA, for the development of multiscale models for complex chemical systems. In the 1970s, Martin Karplus, Michael Levitt and Arieh Warshel laid the foundation for the powerful programs that are used to understand and predict chemical processes. Computer models mirroring real life have become crucial for most advances made in chemistry today.