Chirality is a critical issue in pharmacology for well-known reasons that one enantiomer of an asymmetric molecule is often more active than its counterpart and in some cases one enantiomer has serious side effects. A team from Brookhaven National Laboratory and Ohio University have now turned to nanotechnology in the form of gold-and-silver nanocubes to help them distinguish their lefts from their rights. The nanocubes help the team enhance circular dichroism signals. Our discovery and methods based on this research could be extremely useful for the characterization of biomolecular interactions with drugs, probing protein folding, and in other applications where stereometric properties are important, explains BNL's Oleg Gang.
Hand it to the nanocubes