Enzyme map

Researchers in Spain have used computational chemistry to plot for the first time a cartographic map of enzyme behavior during the catalytic process. Features include the moment when a given enzyme is at the point of maximum energy on the way from taking reactants to final product, which all happens within a femtosecond. The study conducted by researchers at the Universitat Jaume I and the University of Valencia was published in Nature Chemistry. We can [now] make a quantitative estimate of the flexibility of the protein, how much it deforms itself, how much energy you need to deform that protein to generate the reaction that you want, explains UJI's Vicent Moliner.