Chemical correction

The chemical structure of a potentially important marine natural product has been revised based on nuclear magnetic resonance (NMR) spectroscopy and theoretical modeling of the compound. Mary Garson and Gregory Pierens of the University of Queensland, in Brisbane, Australia, and their colleagues in Indonesia and the USA recently reported a stereochemical structural elucidation of the meroterpenoid acremine P from a particular strain of the fungus Acremonium persicinum which was found in the Australian marine sponge Anomoianthella rubra. The revision will not only allow research into this class of compound to move forward it serves as an invaluable reminder that computational studies can help inform structure evaluation and flag up putative incorrect assignments.