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Two-pronged approach to RNA binding
by
Bailey Fallon, RSC
—
last modified
09-04-09 06:51 AM
Copyright 2009, RSC
Combining two RNA-binding ligands gives a conjugate that binds both single and double stranded regions of RNA
The prospect of using RNA as a drug target is of great interest to scientists, but due to its complex structure, designing ligands that bind to it is challenging. Scientists from the University of North Carolina at Chapel Hill, US, have overcome these difficulties by combining two weak ligands to make an RNA-binding conjugate that is far better than the sum of its parts. More...
http://www.rsc.org/Publishing/Journals/cb/Volume/2009/11/rna_binding.asp
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