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Twist in the tale to improve gene therapy

by James Mitchell Crow, RSC last modified 10-14-11 07:42 AM Copyright 2011, RSC
Twist in the tale to improve gene therapy

Plasmid DNA could be a better way to introduce genes into cells © Science Photo Library

New insights into the physical properties of different forms of DNA could help to improve gene therapy, chemists in Spain and India say. Gene therapy aims to cure disease by inserting functional genes into the DNA of living cells, but delivering the DNA into the cell remains a stumbling block. Emilio Aicart, at Universidad Complutense in Madrid, Santanu Bhattacharya, at the Indian Institute of Science in Bangalore, and colleagues say that their findings can explain why some types of DNA can transfect cells more efficiently than others.  More...

http://www.rsc.org/chemistryworld/News/2011/October/14101101.asp

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