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Trifluoromethylation made easy

by Simon Hadlington, RSC last modified 08-15-11 07:42 AM Copyright 2011, RSC
Trifluoromethylation made easy

A new use for an old reagent © Proc. Natl. Acad. Sci. USA

US researchers have discovered a simple, low-cost way to add fluorine atoms to heteroaromatic rings. Inserting fluorine into molecules that are drug candidates can give the compounds many improved properties, such as increased stability or improved interaction with target proteins.  More...

http://www.rsc.org/chemistryworld/News/2011/August/15081102.asp

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