Probing protein aggregation
The tau hypothesis proposes that tangles of tau proteins lead to Alzheimer's disease © National Institutes of Health (NIH)
In 2006 an estimated 26.6 million people worldwide had Alzheimer's disease and those numbers are expected to have quadrupled by the year 2050. Now scientists in the US have developed a probe to better understand protein aggregation processes linked to the disease.
Songi Han at the University of California, Santa Barbara, and co-workers made the nitroxide-based molecule, which can be attached to specific amino acid sites in a protein. More...
http://www.rsc.org/Publishing/Journals/cb/Volume/2009/8/probing_protein_aggregation.asp
