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DNA sequencing on a chip

by Philippa Ross, RSC last modified 02-12-10 10:40 AM Copyright 2010, RSC
DNA sequencing on a chip

An integrated microfluidic device can sequence DNA by denaturation

Scientists in the US have developed a cheap and easy to use DNA sequencing method to help with medical diagnosis. 

Genome sequencing is a costly but important tool in biomedical research used for the study of genetic disease and cancer. Common sequencing methods only sequence one or two DNA bases at a time in several cycles, which makes them costly to run in terms of time and reagents required. Now Xiaohua Huang and colleagues at the University of California, San Diego have come up with a sequencing technique called sequencing by denaturation (SBD), which can be performed on a chip with a single integrated microfluidic device.   More...

http://www.rsc.org/Publishing/Journals/cb/Volume/2010/03/dna_sequencing.asp

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