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Corrections to FRAP diffusion constants in presence of immobile buffer

by Bill Bruno last modified 10-19-06 01:20 PM

New PNAS paper describes an effect where labeled particles (as used in FRAP and other techniques) diffuse slower than the diffusive 'message' does. The formulas derived show how the effect depends on the concentration of immobile "traps".

See: Bernardo Pando, Silvina Ponce Dawson, Don-On Daniel Mak, John E. Pearson Messages diffuse faster than messengers Proc. Natl. Acad. Sci. USA Apr 04, 2006; 103: 5338-5342. Proc. Natl. Acad. Sci. USA Apr 04, 2006; 103: 5338-5342. (This was one of the most read articles in PNAS last month.) Bill
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