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Antiviral Research (v.78, #2)
Antiviral Potency of ST-246 on the Production of Enveloped Orthopoxviruses and Characterization of ST-246 Resistant Vaccinia, Cowpox and Camelpox Viruses
by Sophie Duraffour; Solenne Vigne; Aude Gracel; Robert Jordan; Dennis E. Hruby; Jean-Marc Crance; Daniel Garin; Graciela Andrei; Robert Snoeck (pp. a29-a30).
Serine Side-Chain-linked Peptidomimetic Prodrugs of Cidofovir and Cyclic Cidofovir: C-Ester Effects on Transport and Activation
by Larryn W. Peterson; Boris A. Kashemirov; Ulrika Eriksson; Jae-Seung Kim; Stefanie Mitchell; Paul Kijek; Kyung-Dall Lee; John M. Hilfinger; Charles E. McKenna (pp. a46).
Megaribavirin Aerosol for the Treatment of Influenza A Virus Infections in Mice
by Brian Gilbert; Matthew McLeay (pp. a56-a57).
Synthesis of Structural Analogues of dUY11, A Potent Rigid Amphipathic Fusion Inhibitor Nucleoside
by Stanislav Khramyshev; Olga Valueva; Vladimir Korshun; Alexey Ustinov (pp. a42).
Antiviral Effect of Ingenol and Gingerol During HIV-1 Replication in MT4 Human T Lymphocytes
by Hak Sung Lee; Sung-Soon Kim; Gab Jung Kim; Joo-shil Lee; Eun-Jin Kim; Kee-Jong Hong (pp. a44).
A Microbicide Transmission and Sterilization Assay (MTSA) Defines the Effective Concentration of Topical HIV Microbicides Required to Suppress Virus Transmission
by Karen M. Watson; Christa E. Buckheit; Robert W. Buckheit Jr. (pp. a67).
Assembly of the Immature and Mature Viral Structure as Potential Antiviral Target
by Hans-Georg Krausslich (pp. a18).
Synthesis and Antiviral Activity of Various N4-Acyl Derivatives of Cidofovir and its 5-Azacytosine Counterpart, 1-( S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine
by Marcela Krecmerova; Antonin Holy; Graciela Andrei; Lieve Naesens; Johan Neyts; Jan Balzarini; Erik De Clercq; Robert Snoeck (pp. a59).
Increase of the Effect of Anti-Enteroviral Chemotherapy Used in Experimental Neurotropic Coxsackievirus B1 Infection in Newborn Mice when a Triple Combination of Antivirals is Administered in a Consecutive Treatment Course
by Ralitsa Vassileva-Pencheva; Angel S. Galabov (pp. a66).
PG 301029 Inhibits HCV Replication Through a Novel Late Stage Mechanism of Action
by Todd B. Parsley; Lu Yang; Robert W. Buckheit Jr. (pp. a22).
Development of Resistance to Oxoglaucine in Poliovirus Type 1 (LSc-2ab) and the Six Coxsackie B Viruses
by Lubomira Nikolaeva-Glomb; Angel S. Galabov (pp. a61).
Prodrugs of Antiviral Nucleosides Cleavable by Dipeptidyl-Peptidase-IV (CD26)
by Sonsoles Velázquez; Alberto Diez-Torrubia; M. Teresa Peromingo; Carlos García-Aparicio; Jan Balzarini; María-José Camarasa (pp. a66).
Identification of Halosalicylamide Derivatives as a Novel Class of Allosteric Inhibitors of HCV NS5B Polymerase
by Yaya Liu; Pamela Donner; Wen Jiang; Teresa Ng; Vijaya Gracias; Steve Baumeister; Paul Wiedeman; Linda Traphagen; Usha Warrior; Clarence Maring; Warren Kati; Stevan Djuric; Akhteruzzaman Molla (pp. a21).
Novel Mechanism of Action of Pyrimidinediones Yields Enhanced Sensitivity to Multi-Drug Resistant Virus Strains
by Robert W. Buckheit Jr.; Lu Yang; Tracy L. Hartman; Karen M. Watson (pp. a25-a26).
Check of Antiviral Activity of Nanocomposites with Active Ligand Based on Model of Cattle's Diarrhea Virus (Model of Hepatitis C Virus)
by Viktor Zinoviev; Aleksey Evdokimov; Evgeniy Belanov; Ernst Malygin; Sergey Balachnin; Olga Serova; Dmitriy Pletnev; Valentina Zarytova; Asya Levina; Marina Repkova; Zinfer Ismagilov; Nadegda Shikina; Stanislav Zagrebelnyi; Sergey Baiborodin (pp. a51).
Differential Pathogenesis of Cowpox Virus Intranasal Infections in Mice Induced by Low and High Inoculum Volumes, and Effects of Cidofovir Treatment
by Donald F. Smee; Brian B. Gowen; Miles K. Wandersee; Min-Hui Wong; Ramona T. Skirpstunas; Thomas J. Baldwin; Justin D. Hoopes; Robert W. Sidwell (pp. a64).
Vaccinia DNA Polymerase is Profoundly Inhibited by Cidofovir and ( S)-HPMPA Incorporated into the Template Strand
by Wendy Magee; Karl Hostetler; David Evans (pp. a30).
Synthesis of P–O–C-linked Foscarnet–Peptide Conjugates and Sensitive Methods to Detect the Released Drug in Biological Samples
by Chi V. Pham; Boris A. Kashemirov; Jorge Osuna; Kanokkarn Saejueng; John M. Hilfinger; Charles E. McKenna (pp. a62).
Studying of Anti-Epstein–Barr Virus Activity of Amizon and their Derivative
by Nadiya Nesterova; Svitlana Zagorodnya; Valentina Danilenko; Galina Baranova; Anna Golovan (pp. a61).
Late Stages of the HIV-1 Replication Cycle as Targets for Novel Antiviral Agents
by Eric Freed (pp. a18).
Carbocyclicl-Nucleoside Analogues as Potential Antiviral Agents
by Soenke Jessel; Chris Meier (pp. a58).
Combined Anti-Influenza Virus Effects of a Plant Polyphenol-rich Extract and E-aminocaproic Acid In Vitro and In Vivo
by Julia Serkedjieva; Ani Teodosieva (pp. a64).
Vidarabine Prodrugs as Potential Inhibitors of Adenosine Deaminase
by Brian G. Gentry; Wei Shen; Julie M. Breitenbach; John Hilfinger; John C. Drach (pp. a56).
Evaluation of Interferon Inducers, Ribavirin and Mouse Hyperimmune Serum in a Pathogenesis/Lethal Mouse Model Using a Mouse-adapted SARS-CoV
by Dale Barnard; Craig Day; Miles Wandersee; Yohichi Kumaki; Andres Salazar (pp. a20).
Serine Palmitoyltransferase Inhibitor Suppresses HCV Replication in a Mouse Model
by Yuichi Hirata; Takuya Umehara; Masayuki Sudoh; Fumihiko Yasui; Michinori Kohara (pp. a40).
Chemically Synthesized Tunicamycin Derivatives Effectively Inhibit the Propagation of Classical Swine Fever Virus—A Surrogate Model for Hepatitis C Virus
by Ewelina Krol; Boguslaw Szewczyk; Ilona Wandzik; Grzegorz Grynkiewicz; Wieslaw Szeja (pp. a42-a43).
Anti-Hepatitis C Virus Replicon Activity of Alkoxyalkyl Esters of ( S)-HPMPA and Other Acyclic Nucleoside Phosphonates
by David L. Wyles; Robert T. Schooley; Kelly A. Kaihara; James R. Beadle; Karl Y. Hostetler (pp. a21).
Design, Synthesis and Biological Evaluation of Novel Acyclovir ProTides
by Marco Derudas; Christopher McGuigan; Andrea Brancale; Joachim Bugert; Graciela Andrei; Robert Snoeck; Jan Balzarini (pp. a55-a56).
Susceptibility of Human Cytomegalovirus (HCMV) Drug-resistant Viruses to a New Class of Acyclic Nucleoside Phosphonate Analogues (ANPs)
by Graciela Andrei; Pierre Fiten; Marcela Krecmerova; Antonín Holý; Erik De Clercq; Ghislain Opdenakker; Robert Snoeck (pp. a52).
Suppression of HCV RNA Replication by Baculovirus-mediated shRNA Expression Vectors
by Hitoshi Suzuki; Nobushige Tamai; Kunitada Shimotohno; Yoshiharu Matsuura; Hiroshi Takaku (pp. a49).
Design and Synthesis of Novel Non-nucleoside Anti-HCMV Agents
by R. Adak; C. McGuigan; R. Snoeck; G. Andrei; J. Balzarini; E. Gorovits; C. Chang; B. Ames; Y. Liu; J. Vernachio (pp. a52).
Ring-expanded Nucleosides (RENs) Exhibit Potent ATP-dependent Helicase Activity of RNA Helicase DDX3 with Little or no Toxicity in Ex Vivo Cell Culture or In Vivo in Mice
by Venkat Yedavalli; Ning Zhang; Hongyi Cai; Kuan-Teh Jeang; Ramachandra Hosmane (pp. a68).
Development of a Model for the Study of Antivirals Against Molluscum Contagiosum Virus (MCV)
by Graciela Andrei; Joos Van den Oord; Rita De Vos; Sophie Duraffour; Arlette Blondeel; Thiery Simonart; Erik De Clercq; Robert Snoeck (pp. a30-a31).
Azaindole-based HIV-1 Integrase Specific Inhibitors Display Potent Anti-Retroviral Activity
by Scott Butler; Michael Plewe; Atsuo Kuki; Teddy Johnson; Qinghai Peng; Dorothy Delisle; Joanne Graham; Hua Wu; Amy Patick (pp. a36).
Dysregulation of the Antioxidant Enzyme Defense in Hispanic Women with HIV-associated Neurocognitive Disorder
by Ixane Velazquez; Marines Plaud; Juliana Perez-Laspiur; Richard Skolasky; Valerie Wojna; Loyda Melendez (pp. a50).
Enzyme-triggered CycloSal-Pronucleotides
by Chris Meier; Henning Jessen; Nicolas Gisch; Jan Balzarini (pp. a26).
A Synthetic Strategy to Different Cyclopentenyl-Nucleosides
by Bastian Reichardt; Chris Meier (pp. a62-a63).
HCV RNA Helicase Requirement for NS3 Oligomerization is Substrate-dependent: Characterization of RNA Substrates with Different Double Strand Lengths and RNA Binding-dependent Inhibition
by Julie Hang; Yanli Yang; Vincent Leveque; Tony Giannetti; George Stepan; Nick Cammack; Klaus Klumpp (pp. a23).
Peptide-based Inhibitors of HIV-1 RT Dimerization and Pol-polyprotein Maturation
by Pascal Clayette; Audrey Agopian; Nathalie Dereuddre-Bosquet; Chritine Goffinet; Rahima Yousfi; Jérome Depollier; Karen Storck; Eric Gros; Oliver Keppler; Gilles Divita (pp. a27).
MIV-170, a Novel NNRTI With Potent Activity Against HIV and HIV Mutants
by Bo Öberg; Britt Louise Sahlberg; Christer Sahlberg; Bertil Samuelsson; Kristina Wikström; Lotta Vrang; Hong Zhang (pp. a51).
Stereospecificity, Substrate, and Inhibitory Properties of P-Borano Nucleoside Diphosphates for Creatine, Pyruvate, and NDP Kinases
by Charlotta Wennefors; Mikhail Dobrikov (pp. a67-a68).
Biochemical Evaluation of a New Potential Antiviral Drug HPMP-5-Azacytosine
by Ivan Votruba; Miroslav Hájek; Helena Kaiserová; Eva Tloušťová; Marcela Krečmerová; Antonín Holý (pp. a66-a67).
Low In Vitro Potential for Class-specific Toxicity of GS-9148, A Novel Nucleotide Reverse Transcriptase Inhibitor
by Genevieve Laflamme; Constantin Boojamra; Lijun Zhang; Hon Hui; Robyn Fisher; Richard Mackman; Adrian Ray; Tomas Cihlar (pp. a27).
In Vivo Efficacy of CMX001 Against Herpes Simplex Virus Types 1 and 2
by Debra Quenelle; Deborah Collins; Terri Rice; George Painter; Alice Robertson; Earl Kern (pp. a62).
A Novel NNRTI Class with Potent Anti-HIV Activity Against NNRTI-resistant Viruses
by Anneke Raney; Robert Hamatake; Wen Xu; Jean-Luc Girardet; Jean-Michel Vernier; Li-Tain Yeh; Barry Quart (pp. a47).
Resistance to Pyrimidinedione HIV Inhibitors Requires Multiple Mutations in Reverse Transcriptase, Envelope and Core Proteins
by Robert W. Buckheit Jr.; Christa E. Buckheit; Robert W. Buckheit III; Karen M. Watson (pp. a35-a36).
Evaluation of MK-7009, A Novel Macrocyclic Inhibitor of NS3/4A Protease, in the Chimpanzee Model of Chronic Hepatitis C Virus Infection
by S. Ludmerer; D. Graham; L. Handt; C. Fandozzi; C. Burlein; N. Liverton; J. McCauley; J. Vacca; D. Hazuda; S. Carroll; D. Olsen (pp. a23).
Resistance of Human Cytomegalovirus to Cyclopropavir Involves a Novel Mutation in UL97
by Katherine Z. Borysko; Brian G. Gentry; Julie M. Breitenbach; Jiri Zemlicka; John C. Drach (pp. a54).
Anti-Influenza A Virus Inhibitory Effect of (−)-Epigallocatechin-3- O-Gallate Fatty Acid Monoester Derivatives
by Kunihiro Kaihatsu; Shuichi Mori; Nobuo Kato (pp. a41).
Different Incorporation Efficiencies for Nucleotide Analogs During HCV Polymerase RNA Synthesis Initiation and Elongation Phases
by Han Ma; Nicole Inocencio; Vincent Leveque; Genadiy Kalayanov; David Smith; Nick Cammack; Nils Gunnar Johansson; Klaus Klumpp (pp. a22-a23).
Effects of PTU-23, HBBb, Ribavirin and Oxoglaucine on the Replication of Feline Calicivirus in CrFK Cells
by Julian Tumbarski; Angel S. Galabov (pp. a65).
Herpes Simplex Virus Type 2 Exposed to Rigid Amphipathic Fusion Inhibitors (RAFIs) are not Infectious in a Mouse Vaginal Model
by Mireille St. Vincent; Vladimir Korshun; Alexey Ustinov; Luis Schang (pp. a64-a65).
A Cell-based High-throughput Screening Approach for the Discovery of New Inhibitors of the Influenza H5N1 Virus
by William Severson; Joseph Maddry; Xi Chen; Subramaniam Ananthan; Adrian Poffenberger; Lynn Rasumussen; Melinda Sosa; Lucile White; Diana Noah; Gary Piazza (pp. a48).
Evaluation of C-5 Substituted Uracil Acyclic Phosphonates as Substrates or Inhibitors for DTMP and UMP–CMP Kinases and Potential Antipox Derivatives
by Dimitri Topalis; Julie Broggi; Julie A.C. Alexandre; Ugo Pradère; Vincent Roy; Sabine Berteina-Raboin; Luigi A Agrofoglio; Dominique Deville-Bonne (pp. a65).
Mevastatin Markedly Potentiates the Anti-HCV Activity of Selective Inhibitors of HCV Replication and Delays or Prevents the Emergence of Antiviral Resistance
by Leen Delang; Johan Neyts (pp. a36-a37).
Use of the HCV Cell Culture (HCVcc) System for Antiviral Drug Testing
by Jodi Beattie; Jacob Simmons; Amine Noueiry; Paul Olivo (pp. a35).
Design, Synthesis and Evaluation of 3-Ethynyl-Azole Nucleosides with Antiviral Activity Against Hantaviruses
by Jeffrey Arterburn; Sidath Kumarapperuma; Marjan Jeselnik; Dong-Hoon Chung; Yangie Sun; Willaim Parker; Yong Kyu Chu; Colleen Jonsson (pp. a33).
NAC Reduces Apoptosis and Telomeres Shortening Subsequent to HIV-1 Exposure in an Astrocytoma Cell Line
by Michela Pollicita; Carolina Muscoli; Antonella Sgura; Alberto Biasin; Vincenzo Mollace; Caterina Tanzarella; Claudio Del Duca; Paola Rodinò; Carlo Federico Perno; Stefano Aquaro (pp. a47).
Anti-orthopoxviral activity of the 2-Cycloalkylimino-5-(4-Nitrophenyl)-1,3,4-Thiadiazine Derivatives
by Evgeny Belanov; Lyudmila Sidorova; Vladimir Rusinov; Nikolay Bormotov; Sergey Balakhnin; Olga Serova; Valery Charushin; Oleg Chupakhin (pp. a54).
Immunoprophylaxis of Phleboviral Infection in Hamsters with Recombinant Eimeria Protozoan Surface Antigen
by Kie-Hoon Jung; John W. Judge; Min-Hui Wong; Peter C. Melby; Barnett Rosenberg; John D. Morrey; Brian B. Gowen (pp. a58).
Pth15: An Interfacial Inhibitor of HIV-1 Integrase That Efficiently Blocks HIV-1 Replication
by Edwige Gros; Edwire Guiot; Audrey Agopian; Eric Deprez; Jean Francois Mouscadet; Myriam Witvrouw; Gilles Divita (pp. a28).
Peptide-based Entry Inhibitors for Paramyxoviruses
by Christopher LeBlanc; Russell Wilson; Peter Kulkosky; Robert Garry; Thomas Voss (pp. a43).
Cystatin B Associates with STAT-1 in Monocyte-derived Macrophages and Placental Macrophages: A Possible Link to HIV Activation
by Claribel Luciano-Montalvo; Loyda Melendez-Guerrero (pp. a44).
From RT Inhibitor to RT/IN Dual Inhibitor: An Rational Design
by Zhengqiang Wang; Robert Vince (pp. a51).
Computational Studies of gp41 6-Helix Bundle: Do Stabilized Energy of HIV Membrane Fusion Inhibitor C34 and Interaction Energy of gp41 6-Helix Bundle have Good Correlation with their Inhibitory Activity?
by Norihito Kawashita; Yu-Shi Tian; Masashi Yasuda; U. Chandimal de Silva; Rie Kashiwada; Shota Nakamura; Naohisa Goto; Rika Nishikiori; Kousuke Okamoto; Masanori Kameoka; Teruo Yasunaga; Masaya Kawase; Kazuyoshi Ikuta; Tatsuya Takagi (pp. a42).
Hit QSAR Analysis of Anti-Coxsackievirus B3 Activity of [(Biphenyloxy)Propyl]Isoxazole Derivatives by E. Muratov; V. Kuz’min; A. Artemenko; E. Varlamova; V. Makarov; O. Riabova; P. Wutzler; M. Schmidtke (pp. a60-a61).
Coxsackievirus B3; Selectivity index; QSAR; Drug design
Efficacy of T-1106 or T-705, Alone or in Combination with Ribavirin, in the Treatment of Hamsters Infected with Yellow Fever Virus
by Justin Julander; Kristiina Shafer; Don Smee; John Morrey; Yousuke Furuta (pp. a34).
Developing a Novel High-throughput Screening Assay against Bluetongue Virus
by Qianjun Li; Lynn Rasmussen; Clinton Maddox; E. Lucile White (pp. a59-a60).
Role of Angiogenesis and Wound Repair Factors in the Acceleration of Allograft Rejection by Cytomegalovirus
by Daniel Streblow (pp. a29).
Optimization of shRNA Features for Targeting Hepatitis C Virus
by Brian Johnston; Alexander Vlassov; Brent Korba; Kristine Farrar; Sampa Mukerjee; Attila Seyhan; Heini ILves; Roger Kaspar; Devin Leake; Sergei Kazakov; Qing Ge (pp. a41).
Antiviral Effects of Sulfated Exopolysaccharide from the Marine Microalga Gyrodinium impudicum Strain KG03
by Chong-Kyo Lee; Hae Soo Kim; Ju Ryung Nam; Myung-Jin Lee; Joung-Han Yim; Hong Kum Lee (pp. a59).
Therapies and Mechanisms of West Nile Virus Encephalitis and Neurological Sequelae
by John D. Morrey; Venkatraman Sidharthan; Hong Wang; Neil Motter; Jeffery O. Hall; Robert D. Skinner (pp. a20).
Characterization of a Novel Series of gp120 Inhibitors
by Tanya Parkinson; Peter Stephenson; Chris Pickford; Thien Duc Tran; David Williams; David Fenwick; Juin Fok-Seang; Iain Gardner; Mike Westby; Don Middleton; Manos Perros (pp. a25).
Inhibition of Human Rhinovirus Replication by Some Antivirals
by Irina Georgieva; Angel S. Galabov (pp. a39-a40).
Application of the Phosphoramidate Protide Approach to the Antiviral Drug Ribavirin
by Marco Derudas; Christopher McGuigan; Andrea Brancale; Johan Neyts; Jan Balzarini (pp. a55).
A Novel and Selective Inhibitor of Hepatitis B Virus Surface Antigen Secretion
by Anne Marie Dougherty; Haitao Guo; Gael Westby; Yuanjie Liu; Ju-Tao Guo; Anand S. Mehta; Pamela Norton; Baohua Gu; Timothy M. Block; Andrea Cuconati (pp. a24).
Maribavir Inhibits the Replication of Human Herpesvirus 6 and the Activity of the U69 Protein Kinase
by Mark Prichard; Shannon Daily; Amie Perry; Earl Kern (pp. a29).
New Synthetic Histone Deacetylase Inhibitors CGMC0005 and CGMC0006 Effectively Reactivate Latently Infected Human Immunodeficiency Virus Type-1 (HIV-1) from ACH2 and J1.1 CD4+ T Cells
by Kee-Jong Hong; Sung-Soon Kim; Hak Sung Lee; Joo-Shil Lee; Byeong-Sun Choi (pp. a40-a41).
One-third of the Surface of the Adenovirus Proteinase Contains Potential Drug Targets via a New Paradigm for Virion Maturation
by Walter Mangel (pp. a33-a34).
New Microscopic Description of Herpes Virus–Cell Dynamic System
by Oleksandr Fedchuk; Alla Fedchuk; Iryna Bartsykovska; Andriy Fedchuk (pp. a38).
Peptide-based Entry Inhibitors for Influenza
by Thomas Voss; Christopher LeBlanc; Joseph Barbercheck; Bryan Kaplan; Russell Wilson; Garry Robert (pp. a18).
Discovery of a Novel HCV Helicase Inhibitor by a De Novo Drug Design Approach
by Andrea Brancale; Dimitrios Vlachakis; Sahar Kandil; Sonia Biondaro; Colin Berry; Johan Neyts (pp. a22).
Characterization of Small Molecule Inhibitors of West Nile Virus NS3 Serine Protease
by Prasanth Viswanathan; Niklaus Mueller; Nagarajan Pattabiraman; Kyungae Lee; Gregory Cuny; Ratree Takhampunya1; Camilo Ansarah-Sabrino; Theodore Pierson; R. Padmanabhan (pp. a50).
Novel Five-membered Ring Imino Sugar Derivatives Inhibit Flaviviruses via Distinct Mechanisms
by Jinhong Chang; Lijuan Wang; Dongling Ma; Robert Moriarty; Benjamin Davis; Peter Mason; Baohua Gu; Xiaodong Xu; Ju-Tao Guo; Timothy Block (pp. a24).
QSAR Analysis of Cytotoxicity in HeLa Cells
by V. Kuz’min; A. Artemenko; E. Muratov; E. Varlamova; V. Makarov; O. Riabova; P. Wutzler; M. Schmidtke (pp. a43).
Synthesis and Evaluation of Octadecyloxyethyl Esters of Five 3-Hydroxy-2-(Phosphonomethoxy)Propyl Nucleoside Phosphonates in HIV-1 Infected Cells
by Nadejda Valiaeva; Kathy A. Aldern; Julissa Trahan; James R. Beadle; Karl Y. Hostetler (pp. a49-a50).
Design, Synthesis and Evaluation of Novel Anti-VZV BCNAs
by Christopher McGuigan; Marco Migliore; Geoffrey Henson; Joseph Patti; Graciela Andrei; Robert Snoeck; Jan Balzarini (pp. a29).
In Vitro and In Vivo Efficacy of a Pyrimidine Nucleoside Analog Against Vaccinia and Cowpox Viruses
by Debra Quenelle; Mark Prichard; Kathy Keith; Deborah Collins; Terri Rice; John Secrist; Kamal Tiwari; Joseph Maddry; Earl Kern (pp. a31).
Sub-optimal Protease Inhibition of HIV-1: Effects on Virion Morphogenesis and RNA Maturation
by Michael D. Moore; William Fu; Roger G. Ptak; Wei-Shau Hu (pp. a45).
Inhibition of Human T-Cell Lymphotropic Virus Type-1 Integrase by Dicaffeoylquinic Acids Extracted from Coffee ( Coffea arabica) Seeds
by Ordonez Paula; Panay Joel; Cuesta-Astroz Yesid; Ceballos Carolina; Ceron Flavio; Moncayo Alejandro; Martha C. Dominguez; Sanchez Adalberto; Lareo Leonardo; Garcia-Vallejo Felipe (pp. a45-a46).
Significance of 3b-dehydroxysterol-D24-reductase (DHCR24) in life cycle of Hepatitis C virus
by Tomohiro Nishimura; Masaaki Sato; Makoto Saito; Yuri Kasama; Michinori Kohara; Kyoko Kohara (pp. a45).
Development of the Dual-Acting Pyrimidinedione IQP0528 as a Vaginal Topical Anti-HIV Microbicide
by Karen M. Watson; Lu Yang; Christa E. Buckheit; Robert W. Buckheit Jr. (pp. a26).
Antioxidant Properties of Oseltamivir—A Specific Na Inhibitor of Influenza Virus Infection Type A in Influenza Virus Infected Mice and in some Model Systems
by Milka Mileva; Angel S. Galabov; Lora Simeonova; Galina Gegova (pp. a60).
Synthesis and Properties of Glycosyl-functionalised CycloSal–Pronucleotides
by Tilmann Schulz; Jan Balzarini; Chris Meier (pp. a63).
Dielectric Spectroscopy as a Tool for Virus–Cell Interaction Rate Description
by Oleksandr Fedchuk; Andriy Fedchuk; Iryna Bartsykovska; Alla Fedchuk (pp. a38-a39).
A Recombinant, Infectious Human Parainfluenza Virus Type 3 Expressing the Enhanced Green Fluorescent Protein for Use in High Throughput Antiviral Assays
by Jason P. Roth; Donald F. Smee; Dale L. Barnard (pp. a47-a48).
Single-Dose Safety and Pharmacokinetics of ST-246, A Novel Orthopoxvirus Egress Inhibitor
by Robert Jordan; Kevin Jones; Tove’ Bolken; Deborah Tien; Josef Strasser; T.R. Shanthakumar; Annie Frimm; Michael Corrado; Phoebe Strome; Dennis Hruby (pp. a32).
Comparative Virtual and Experimental Medium Throughput Screening for Hepatitis C Virus Polymerase Inhibitors
by Helene Dutartre; Cecile Bussetta; Stephane Betzi; Joelle Boretto-Soler; Claire Debarnot; Mohamed Ben-Rahou; Jean-Louis Romette; Jean Claude Guillemot; Karine Alvarez; Xavier Morelli; Bruno Canard (pp. a37).
Placental and Monocyte-derived Macrophages have Different Secretome
by Katia Garcia; Vivian Garcia; Juliana Perez; Fenghai Duan; Loyda Melendez (pp. a39).
Check of Antiviral Activity of Nanocomposites with Active Check of Antiviral Activity of Drugs Based on Nanocomposites, Which Contained Oligonucleotides for Direct Splitting Viral Genome of Influenza Virus Type A
by Dmitriy Pletnev; Aleksei Evdokimov; Evgeniy Belanov; Ernst Malygin; Sergey Balachnin; Olga Serova; Viktor Zinoviev; Valentina Zarytova; Asya Levina; Marina Repkova; Zinfer Ismagilov; Nadegda Shikina; Stanislav Zagrebelnyi; Sergey Baiborodin (pp. a46).
MIV-170, A Novel NNRTI Exhibiting Tight Binding to HIV-1 Reverse Transcriptase (RT)
by Malin Elinder; Helena Danielson; Torsten Unge; Guido VanHam; Bo Öberg (pp. a37).
NGO Analysis of Impact of HIV Infection and Antiretroviral Therapies in Resource Poor Nations
by Pramod Sankapal; Vaishali Sankapal; Nirmal Rawandale (pp. a48).
Use of AX-4 Cells for the Study of the Pharmacodynamics of Oseltamivir Carboxylate for Influenza Viruses in an In Vitro Hollow Fiber Infection Model System
by James McSharry; Qingmei Weng; Kate Soldani; Kris Zager (pp. a44-a45).
Broad Anti-Infective Activity of Viracea, An Echinacea-derived Product
by Tracy L. Hartman; Karen M. Watson; Lu Yang; Meryl J. Squires; Robert W. Buckheit Jr. (pp. a40).
Influence of Hsp70 on HIV-1 Infection
by Ryuichi Sugiyama; Yuichiro Habu; Haruki Naganuma; Hiroshi Takaku (pp. a49).
In Vitro Vascular Leak as a Model of Viral Hemorrhagic Fever
by Rebecca Brocato; Voss Thomas (pp. a35).
Cyclopentenylcytosine (CPE-C) Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model
by Eric G. Romanowski; Kathleen A. Yates; Y. Jerold Gordon (pp. a63).
Inverse Wavelet Transform in Virus–Cell Interaction Imaging
by Andriy Fedchuk; Iryna Bartsykovska; Alla Fedchuk; Oleksandr Fedchuk (pp. a38).
Synthesis and Activity of Vidarabined-Amino Acid Prodrugs as Potential Pox Virus Agents
by Julie M. Breitenbach; Wei Shen; John Hilfinger; John C. Drach (pp. a54-a55).
Establishment of a Cell-based HTS System for Discovery of Anti-Flavivirus Drugs
by Yali Chen; Chris Harver; Travis Warren; Dennis Hruby; Robert Jordan (pp. a36).
LEDGF/P75 as a Co-factor of HIV-1 Integrase and as a New Antiviral Target
by Zeger Debyser (pp. a18).
Development of Novel Selective Parainfluenza Virus Hemagglutinin–Neuraminidase Inhibitors
by Irina V. Alymova; Makiko Watanabe; Vasiliy P. Mishin; Y. Sudhakara Babu; Allen Portner (pp. a19-a20).
A Single Accelerating Dose Study to Evaluate Safety and Pharmacokinetics (PK) of FV-100 in Healthy Subjects
by S.M. Canas; B. Wargin; B. Boehlecke; G. Henson; J.M. Patti; A.M. Morris (pp. a32).
AlphaV Integrin-mediated Adhesion of Monocyte-derived Macrophages Influences HIV Infection
by Ester Ballana; Eduardo Pauls; Imma Clotet-Codina; Berta Bosch; Françoise Perron-Sierra; Gordon Tucker; Bonaventura Clotet; Jose Esté (pp. a34-a35).
Novel Inhibitors of Orthopoxvirus Replication Target Vaccinia Virus P37 Envelope Protein
by Kathy A. Keith; Debra C. Quenelle; Shalisa Sanders; Robin C. Conley; Earl R. Kern; Mark N. Prichard (pp. a58-a59).
Inhibition of HIV-1 Infection in Hu–PBL–SCID Reconstituted Mice by Rapamacyn
by Stefano Aquaro; Caterina Lapenta; Filippo Belardelli; Carlo-Federico Perno; Ferdinando Nicoletti (pp. a53).
Luciferase-based Assay for Rapid Screening of Antivirals against Human Cytomegalovirus
by Caroll Hartline; Earl Kern (pp. a57-a58).
Preclinical Development of the Amphipathic DNA Polymer REP 9AC for the Treatment of Hepatitis B Virus Infection
by Faseeha Noordeen; Andrew Vaillant; Jean-Marc Juteau; Allison Jilbert (pp. a25).
Efficacy of Therapeutic Intervention with an Oral Ether Lipid Analogue of Cidofovir (CMX001) in a Lethal Mousepox Model
by Scott Parker; Christina Oberle; Erin Touchette; R. Mark Buller (pp. a61-a62).
Effect of Treatment with the Cidofovir Analogue HDP-CDV in Guinea Pig Models of Cytomegalovirus Infection
by Fernando Bravo; Rhonda Cardin; Karl Hostetler; David Bernstein (pp. a31).
Factors Affecting Susceptibility of H5N1 Influenza Viruses to Neuraminidase Inhibitor Oseltamivir
by Elena Govorkova; Natalia Ilyushina; Jennifer McClaren; Tri Naipospos; Neziha Yilmas; Bounlom Douangngeun; Robert Webster (pp. a18-a19).
A Derivate of the Antibiotic Doxorubicin Inhibits Dengue and Yellow Fever Virus Replication In Vitro
by Suzanne Kaptein; Michael Jacobs; Andrea Gamarnik; Erik De Clercq; Ferenc Sztaricskai; Johan Neyts (pp. a33).
Therapy of Advanced Arenaviral Infection in Hamsters with T-705
by Brian Gowen; Min-Hui Wong; Kie-Hoon Jung; Kevin Bailey; Yousuke Furuta; John Morrey (pp. a57).
In Vivo Synergistic Combination Effect of Rimantadine and Oseltamivir Against Influenza A(H3N2) is Manifested in Several Dose Ratios
by Lora Simeonova; Angel S. Galabov; Galina Gegova (pp. a19).
Synthesis, Antiviral and Cytotoxic Activities of SomeNovel 2,3-Disubstituted Quinazolin-4(3H)-Ones
by Periyasamy Selvam; Padamraj Rathore; P. Babu; Leentje Persoons; Erik de Clercq (pp. a64).
Virucidal Activity of Extracts from Four Algae Species Against Herpes Simplex Virus
by Emma Harden; Caroll Hartline; Ruth Falshaw; Susan Carnachan; Earl Kern; Mark Prichard (pp. a57).
Antiviral Activity of (−)-d-Carbocyclic Cytosine (Carbodine) Against Avian Influenza Virus (H5N1)
by C.K. Chu; J. Rao; C.W. Day; D.L. Barnard; D.F. Smee (pp. a55).
QSAR Analysis of Influence of Artifical Ribonucleases Structure on their Anti-influenza Activity
by A. Artemenko; V. Kuz’min; E. Muratov; M. Kulinskiy; V. Lozitsky; A. Fedchuk; T. Gridina; L. Koroleva; V. Silnikov (pp. a53).
Effective Small Interfering RNAs Targeting AlphaV Integrin Inhibit HIV-1 Replication
by Eduardo Pauls; Ester Ballana; Imma Clotet-Codina; Berta Bosch; Françoise Perron-Sierra; Gordon Tucker; Bonaventura Clotet; Jose Esté (pp. a28).
