Forgot your password?
New user?
Development and Manufacture of Effervescent Tablets
Thermal Methods and Calorimetry - applications and practical help
Document Actions
The Challenges and Formulation Strategies for Poorly Soluble Drug Substances
| Type | Training - Paid |
|---|---|
| Language | English |
| Date |
May 21, 2007
to May 22, 2007 |
| Venue |
Thistle Westminster Hotel Buckingham Palace Road London, GB |
| Chemistry Specialties |
|
| Chemistry Techniques |
|
| Contact |
Judy Callanan PharmaTraining Services 1st Floor, 77 Leonard Street London, EC2A 4QS GB 0044 20 7613 7232 0044 20 7681 3582 judy@pharmatrainingservices.com |
| Add event to calendar |
vCal (Windows, Linux)
iCal (Mac OS X)
|
Many, if not most, new active pharmaceutical ingredients have very low aqueous solubility, and this will have a negative impact on their value as potential medicines. This course is designed to describe the basic theory and to develop from there with a strategy for dealing with poorly soluble compounds. Firstly considering salts and physical form changes (including some discussion of intellectual property and regulatory issues), then progressing to consider amorphous solid dispersion systems (their advantages, potential problems and how to make a success of such formulations), then to reflect on lipid based formulations, solubilisation approaches and self emulsifying systems. The course is well suited to those new to the formulation of poorly soluble drugs, either with or without extensive formulation experience in other areas, as well as those working in materials characterisation and preformulation.