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Introduction to Photostability
A Practical Introduction to
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The Challenges and Formulation Strategies for Poorly Soluble Drug Substances
| Type | Course |
|---|---|
| Language | English |
| Date |
October 11, 2007
to October 12, 2007 |
| Venue |
The Baltic Exchange 1st Floor London, EC2A 4QS GB |
| Chemistry Specialties |
|
| Chemistry Techniques |
|
| Contact |
judy@pharmatrainingservices.com PharmaTraining Services 1st Floor London, EC2A 4QS GB 0044 20 7613 7232 0044 20 7681 3582 judy@pharmatrainingservices.com |
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Many, if not most, new active pharmaceutical ingredients have very low aqueous solubility, and this will have a negative impact on their value as potential medicines. This course is designed to describe the basic theory and to develop from there with a strategy for dealing with poorly soluble compounds. Firstly considering salts and physical form changes (including some discussion of intellectual property and regulatory issues), then progressing to consider amorphous solid dispersion systems (their advantages, potential problems and how to make a success of such formulations), then to reflect on lipid based formulations, solubilisation approaches and self emulsifying systems. The course is well suited to those new to the formulation of poorly soluble drugs, either with or without extensive formulation experience in other areas, as well as those working in materials characterisation and preformulation