Symposium on Extracellular and Membrane Proteases in Cell Signaling

Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University; Mayo Clinic Cancer Center; Vanderbilt University Medical Center; Office of Biotechnology, Iowa State University

Lynn Matrisian: Vanderbilt University, Nashville, Tennessee Matrix Metalloproteinases as mediators of cellular communication Mien-Chie Hung: MD Anderson Cancer Center, Houston, Texas A novel mechanism for nuclear translocation of receptor tyrosine kinases Carl Blobel: Cornell University, New York ADAMs, key molecules in EGF-receptor signaling Conor Lynch: Vanderbilt University, Nashville, Tennessee MMPs: Essential regulators of the vicious cycle of bone metastasis Bin-Bing Zhou: Wyeth Pharmaceutical, Pearl River, New York Targeting ADAM-mediated Signaling for Cancer Drug Discovery Howard Crawford: SUNY Stony Brook, New York Notch Activation by ADAMs and MMPs in Pancreatic Disease Matthew Freeman: MRC Laboratory of Molecular Biology, Cambridge, UK Rhomboids and growth factor signalling JoAnn Trejo: University of North Carolina - Chapel Hill Regulation of Protease-activated Receptor Signaling Wolfram Ruf: The Scripps Research Institute (TSRI), La Jolla, California Regulation of Inflammation by Protease Signaling Heidi Hamm: Vanderbilt University, Nashville, Tennessee Thrombin-mediated G protein signaling pathways Athan Kuliopulos: Tufts - New England Medical Center, Boston, MA Metalloprotease-PAR1 Signaling in Cancer Invasion and Angiogenesis Chris Overall: University of British Columbia, Vancouver, Canada Signaling Change: New Roles For Proteases Revealed by Degradomics Bill Parks: University of Washington, Seattle, Washington Regulation of Innate Immunity by MMPs Stella Tsirka: University Medical Center at Stony Brook, New York Tissue plasminogen activator and microglia activation in neurodegenerative disease Thomas Bugge: National Institutes of Health, Bethesda, Maryland The intracellular pathway of collagen degradation in tissue development and malignancy Luisa Iruela-Arispe: UCLA, Los Angeles, California Intersection of growth factors and extracellular matrix during vascular morphogenesis Steve Weiss: Life Sciences Institute, Ann Arbor, Michigan MT-MMP-Dependent Remodeling of the Extracellular Matrix Valerie Weaver: University of California - San Francisco, California Influence of extracellular matrix composition and organization during development and tumorigenesis