Pharmaceutical Physical Form - Amorphous and Polymorphic Forms

Type	Training - Paid
Language	English
Date	June 25, 2007 to June 26, 2007
Venue	British Institute of Radiology Portland Street London, GB
Chemistry Specialties	solid state chemistry and materials science
Chemistry Techniques	other
Contact	Judy Callanan PharmaTraining Services 1st Floor, 77 Leonard Street London, EC2A 4QS GB 0044 20 7613 7232 0044 20 7681 3582 judy@pharmatrainingservices.com
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It is well known that different physical forms of materials can result in changes in bioavailability, as well as chemical stability and processability. As well as these critical changes, that impact on ease of manufacture, storage and use of pharmaceuticals, there are also vital issues with respect to intellectual property which have great commercial significance. In this course we will study the nature of the physical form, how it is produced, techniques for detection and optimisation of behaviour. With respect to the amorphous from we will consider quantification, understanding of relaxation (which brings changes in properties with time), how to remove unwanted amorphous material, then how to keep wanted amorphous forms in that state and finally regulatory and IP considerations of the solid state will be reviewed.

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