Kinetics of Enzyme Action - Basic Principles for Drug Hunters
| Type | Course |
|---|---|
| Language | English |
| Date |
April 5, 2008
to April 6, 2008 |
| Venue |
Doubletree New Orleans 300 Canal St New Orleans, LA 70130 US |
| Chemistry Specialties |
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| Chemistry Techniques |
|
| Contact |
ACS 1155 Sixteenth Street, NW Washington, DC , 20036 US 1-800-227-5558 ext. 4508 202-872-6336 service@acs.org |
| Add event to calendar |
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This course covers the essentials of enzyme kinetic analysis emphasizing concepts of importance in drug discovery. It provides an introduction to enzymology, assay methods, and free-energy diagrams; and also covers simple reversible inhibition and time-dependent inhibition; transition state rate theory and TS analog inhibitors; kinetics and inhibition of two substrate enzymatic reactions; screening for inhibitors of enzymatic reactions; and, probes of mechanism.
Key Topics
* Enzymology, Assay Methods, and Free-Energy Diagrams
* Concepts of Simple Reversible Inhibition
* Time-Dependent Inhibition
* Transition State Rate Theory and TS Analog Inhibitors
* Kinetics of Two Substrate Enzymatic Reactions
* Inhibition of Two-Substrate Enzymatic Reactions
* Screening for Inhibitors of Enzymatic Reactions
* Probes of Mechanism
Speakers
Ross Stein is an Associate Professor in the Department of Neurology at Harvard Medical School and Director of the Laboratory for Drug Discovery in Neurodegeneration of the Harvard Center for Neurodegeneration and Repair. Dr. Stein has been a practicing enzymologist for nearly 30 years and has published over 90 research papers on no less than a dozen different enzyme systems. Before joining Harvard in 2001, he spent 20 years building and running Enzymology and Biochemistry departments in the pharmaceutical and biotech industry.
Cost
Member - $1095
Academic Member - $547.50
Note: This discount is only available if you register by fax, mail or phone and mention this discount and may not be combined with any other offer.
Nonmember - $1,245
Early Registration - Register before March 3, 2008 for the ACS Spring National Meeting Short Courses and receive $100 off the standard member/nonmember fees
Late Registration - Registrations after March 31, 2008 for the ACS Spring National Meeting Short Courses will be assessed a $100 administrative fee
Group Rate - Five for Four! Register five people for one course, one person for five courses, or any combination in between and your fifth registration is free.
Note: This discount is only available if you register by fax, mail or phone and mention this discount and may not be combined with any other offer.
