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Introduction to Modern Mass Spectrometry

Type Course
Language English
Date August 15, 2009 to
August 16, 2009
Venue Four Points By Sheraton
1201 K Street NW
Washington, DC 20005
US
Chemistry Specialties
  • spectroscopy
Chemistry Techniques
  • mass spectroscopy
Contact
American Chemical Society
1155 Sixteenth Street, NW
Washington, DC 20036
US
(800) 227-5558

shortcourses@acs.org
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by Daniel Fishman last modified 05-26-09 04:25 AM

This course covers mass spectrometry fundamentals as well as the latest developments in the field, with emphasis on biological and biochemical applications. You will: learn strategic procedures followed by mass spectrometrists; improve the way you approach solving an analytical problem by mass spectrometry; learn about interfacing chromatographic procedures with mass spectrometry; and learn peripheral technologies required for mass spectrometry.

* Deciding the best techniques for you sample analysis. * Detection of gaseous ions. * Fragmentation of ions. * Obtaining quantitative data from your sample. * Separation of ions according to mass. * Strengths and limitations of mass spectrometry.

Session titles

* Review of spectroscopic techniques * Basic concepts of Mass Spectrometry * Mass Spectrometric Detectors, Analyzers (magnetic, quadrupole, ion trap, TOF, FTMS, orbitrap), ionization Techniques (EI, CI, DCI, FD, ICP, FAB, ESI, nanospray, sonic-spray, APPI, APCI, MALDI, SELDI), IRMS * Mass Spectrometric Terms * Data Acquisition Techniques * Molecular ion and molecular formulas * Accurate mass determination (lockspray), isotopes and isotope abundances * Multiply charged ions. Molecular weight determination of large molecules such as proteins * Collision-induced dissociation (CID), post-source decay (PSD), MS/MS, and linked scans * Interfacing GC, LC, and other separation techniques with mass spectrometry * Quantification (SIM, MRM). Environmental, Biological, Pharmacological, Forensic, and Geochemical Applications

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